1, 5-dicaffeoylquinic acid, an α-glucosidase inhibitor from the root of Dorema ammoniacum D. Don
نویسندگان
چکیده
منابع مشابه
تعیین مناسبترین مدت سرمادهی و عمق کاشت بذر وشا (.Dorema ammoniacum D. Don)
بذرهای گیاه وشا از منظقه ساران دماوند در اواسط تیر ماه 1380 جمع آوری گردید و برای تعیین مدت مناسب برای سرمادهی ، دوره های سرمادهی 0، 20، 25، 30، 35 روز، انتخاب شد .درجه حرارت تیمارهای سرمادهی 3-4 درجه سانتیگراد بود و تیمار شاهد در شرایط متعارف آزمایشگاهی قرار داده شد . بذرهای تیمار شده در پتری دیش کاشته شدند و پس از طی دوره سرمادهی به گلدان منتقل شدند و برای هر تیمار 5 تکرار کشت شد . پس از دو ...
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The potent α-glucosidase inhibitor (compound I) was isolated from coffee brews by the activity-based fractionation and identified as a β-carboline alkaloid norharman (9H-pyrido[ 3.4-b]indole) on the basis of mass spectroscopy and nuclear magnetic resonance spectra ((1)H NMR, (13)C NMR, and COSY). The norharman showed a potent inhibition against α-glucosidase enzyme in a concentration dependent ...
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A soil microorganism producing αand β-glucosidase inhibitors was identified as Bacillus lentimorbus, based on the fatty acid and morphological analyses, along with biochemical and physiological tests. The α-glucosidase inhibitor was highly produced by this strain in a culture medium containing 0.25% of sodium glutamate and 0.5% of glucose, pH 8.0 at 30C for 2 days. The α-glucosidase inhibitor f...
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This study investigated the anticonvulsant activity and possible mechanism of action of an aqueous solution of Dorema ammoniacum gum (DAG) which has been used traditionally in the treatment of convulsions. In this study, the anticonvulsant activity of DAG was examined using the pentylentetrazole (PTZ) model in mice. Thirty male albino mice were divided randomly and equally to 5 groups, and pret...
متن کاملIsolation and characterization of an α-glucosidase inhibitor from Musa spp. (Baxijiao) flowers.
The use of α-glucosidase inhibitors is considered to be an effective strategy in the treatment of diabetes. Using a bioassay-guided fractionation technique, five Bacillus stearothermophilus α-glucosidase inhibitors were isolated from the flowers of Musa spp. (Baxijiao). Using NMR spectroscopy analysis they were identified as vanillic acid (1), ferulic acid (2), β-sitosterol (3), daucosterol (4)...
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ژورنال
عنوان ژورنال: Research in Pharmaceutical Sciences
سال: 2020
ISSN: 1735-5362
DOI: 10.4103/1735-5362.297845